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| Management number | 204569861 | Release Date | 2025/10/14 | List Price | $25.26 | Model Number | 204569861 | ||
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Simparica Trio for Dogs 44.1-88 lbs is a once-monthly liver-flavored chewable delivering three-in-one defense against fleas, ticks, and heartworm disease while treating roundworms and hookworms. Its rapid-action sarolaner, moxidectin, and pyrantel pamoate combination ensures broad-spectrum parasite control in a single tasty dose.
Sarolaner, Moxidectin, Pyrantel Pamoate
Beef liver flavor, microcrystalline cellulose, silicon dioxide, magnesium stearate, other pharmaceutical excipients
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Variants |
Active Ingredients |
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|
Weight Range |
Box Label Color |
Sarolaner (mg) |
Moxidectin (mg) |
Pyrantel (mg) |
|
2.8-5.5 lbs |
Yellow |
5 mg |
0.1 mg |
20 mg |
|
5.6-11 lbs |
Purple |
10 mg |
0.2 mg |
50 mg |
|
11.1-22 lbs |
Orange |
20 mg |
0.4 mg |
100 mg |
|
22.1-44 lbs |
Blue |
40 mg |
0.8 mg |
200 mg |
|
44.1-88 lbs |
Green |
48 mg |
0.96 mg |
200 mg |
|
88.1-132 lbs |
Brown |
56 mg |
1.12 mg |
200 mg |
We offer ground, express, priority, and international delivery; see our shipping policy for details.
For return instructions or product concerns, please refer to our detailed refund policy.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Ans: Simparica Trio begins eliminating adult fleas within 4 hours and five species of disease-carrying ticks within 8 hours after oral administration. This rapid action helps interrupt parasite feeding and reproduction, providing continuous protection throughout the full 30-day dosing interval.
Ans: Yes, Simparica Trio may be administered alongside veterinarian-prescribed heartworm, tick, or mite preventives without compromising safety or efficacy. Always inform your veterinarian of all current medications and products your dog uses to avoid potential interactions or overlapping treatments.
Ans: If you miss a scheduled monthly dose, administer Simparica Trio as soon as you remember and then continue with the regular monthly schedule. Do not give two tablets on the same day to catch up, as this may increase the risk of adverse reactions.
Ans: Use caution when administering Simparica Trio to dogs with a history of seizures or neurological disorders. Consult your veterinarian before initiating treatment to assess potential risks and monitor your pet closely for any unusual behaviors or neurological symptoms post-administration.
Ans: Yes, a negative heartworm test is required before the first Simparica Trio administration to ensure safety. Starting treatment in an infected dog can lead to serious complications as the medication eliminates existing larval heartworms from the bloodstream.
If you notice any omissions or errors in the product information on this page, please use the correction request form below.
Correction Request Form